22 July 2008

Dimebon for Dementia?

This looks interesting....
A single 20mg pill of the drug, called Dimebon, taken three times a day, appears to be twice as effective in improving cognitive performance and preventing deterioration in memory as existing drugs.

The discovery was greeted by charities as perhaps the most exciting development in treatment of the disease. Existing drugs --- cholinesterase inhibitors such as Aricept --- have limited effects and were introduced over a decade ago.

According to the American researchers who led the trial, Dimebon is the furthest advanced of 65 agents being investigated for Alzheimer's, and holds the most promise.
~ The Independent, 22 July 2008

Dimebon is Dimebolin Hydrochloride, and was used as an antihistamine in Russia 20 years ago. It was taken off the market when newer drugs came in the picture.

Recently, it has been shown that Dimebon may inhibit brain-cell death and may improve the clinical outcome of patients suffering from mild to moderate Alzheimer's Disease.

In healthy people, studies have suggested that Dimebon may have "cognition-enhancing effects," and may prove to be a potential nootropic, or a compound that can greatly improve brain function.
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